Mangiferin

Mangiferin is a natural compound primarily found in the leaves, bark, and fruit of mango trees (Mangifera indica). It belongs to a class of phytochemicals known as xanthones, which are potent antioxidants. Mangiferin has garnered significant interest in the field of medicine due to its various potential health benefits.

1. Antioxidant Properties: Mangiferin exhibits strong antioxidant activity, which helps in neutralizing harmful free radicals in the body. This property is believed to contribute to its protective effects against oxidative stress-related diseases.
2. Anti-inflammatory Effects: Studies suggest that mangiferin possesses anti-inflammatory properties, which may help in reducing inflammation and alleviating symptoms associated with inflammatory conditions such as arthritis and inflammatory bowel disease.
3. Antidiabetic Activity: Mangiferin has been investigated for its potential in managing diabetes. It may help in regulating blood sugar levels by improving insulin sensitivity, enhancing glucose uptake by cells, and inhibiting certain enzymes involved in carbohydrate metabolism.
4. Cardioprotective Effects: Research indicates that mangiferin may offer protection against cardiovascular diseases by exerting beneficial effects on various cardiovascular risk factors. It may help in reducing cholesterol levels, improving lipid metabolism, and preventing the formation of arterial plaques.
5. Neuroprotective Properties: Mangiferin has shown promise in protecting the brain against neurodegenerative diseases such as Alzheimer's and Parkinson's disease. Its antioxidant and anti-inflammatory actions may help preserve neuronal function and reducetumours cognitive decline.
6. Anticancer Potential: Some studies suggest that mangiferin exhibits anticancer properties by inhibiting the growth of cancer cells, inducing apoptosis (cell death) in cancer cells, and preventing the spread of tumors. However, more research is needed to fully understand its mechanisms of action and potential applications in cancer therapy.