Khellin is a naturally occurring compound found in the seeds of the plant Ammi visnaga, also known as khella. This compound has been used for medicinal purposes for centuries, particularly in traditional medicine practices in the Middle East and North Africa.
One of the most notable medicinal properties of khellin is its vasodilatory effects, which means it can widen blood vessels. This property has led to its use in the treatment of various cardiovascular conditions, such as angina pectoris (chest pain due to reduced blood flow to the heart) and certain types of heart arrhythmias. By dilating blood vessels, khellin can help improve blood flow to the heart and reduce the workload on the heart muscle.
Khellin works by inhibiting the activity of calcium ions in smooth muscle cells, which are involved in the contraction of blood vessels. By blocking calcium channels, khellin helps relax the smooth muscles in the walls of blood vessels, leading to their dilation and increased blood flow.
In addition to its cardiovascular effects, khellin has also been studied for its potential anti-inflammatory and bronchodilator properties. Some research suggests that it may have applications in the treatment of asthma and other respiratory conditions.
However, it's important to note that while khellin has shown promise in preliminary studies, more research is needed to fully understand its effectiveness and safety profile, particularly in long-term use and in different patient populations. As with any medicinal compound, it should be used under the supervision of a qualified healthcare professional.