Isoquercetin, isoquercitrin or isotrifoliin is a flavonoid, a type of chemical compound. It is the 3-O-glucoside of quercetin.
Isoquercetin is a flavonoid compound, a subclass of flavonols, that is found in various plants such as fruits, vegetables, and grains. It is a glycoside of quercetin, meaning that it is quercetin bound to a sugar molecule, specifically glucose. This linkage with glucose enhances its bioavailability compared to quercetin alone.
Chemically, isoquercetin can be represented as 3-O-beta-D-glucosylquercetin or quercetin-3-O-glucoside. Structurally, it consists of a flavonoid core with three hydroxyl groups (OH) attached to the flavone backbone, and it also contains a glucose moiety attached at position 3.
Isoquercetin is known for its antioxidant properties, which contribute to its potential health benefits. It has been studied for its anti-inflammatory, anti-allergic, anti-cancer, and neuroprotective effects, among others. Due to its ability to scavenge free radicals and modulate various cellular processes, isoquercetin has garnered interest in both pharmaceutical and nutraceutical industries.