Fumaric acid

International Numbering System (INS) for Food Additives: 297
Food additives Europe numbers: E297

Fumaric acid is a type of organic acid found naturally in some fruits and used as a food additive. In medicine, it is used for the treatment of psoriasis and other skin conditions. It is believed to act by decreasing inflammation and regulating the body's immune response. Fumaric acid is available in topical creams, gels, and solutions, as well as in oral tablets and capsules.

Fumaric acid itself isn't actually a commonly used medication, but it plays a role in some treatments. Here's what you need to know:

Function:

  • Fumaric acid is an organic acid found naturally in some foods and produced by the body during certain metabolic processes.

Medical Applications:

  • Fumaric acid esters: These are chemically modified forms of fumaric acid. One such ester, dimethyl fumarate, is the active ingredient in the medication Tecfidera, approved to treat relapsing-remitting multiple sclerosis. Fumaric acid esters are thought to work by modulating the immune system and reducing inflammation.
  • Psoriasis treatment: While not directly used itself, fumaric acid esters have been used historically for the treatment of psoriasis in some countries.

Important Points:

  • Fumaric acid itself is not a medication and shouldn't be taken for any medical condition without consulting a doctor.
  • Fumaric acid esters, like dimethyl fumarate, can have side effects and require a doctor's prescription.

Additional Information:

  • Fumaric acid is generally safe in food but can cause stomach upset in high concentrations.

In Summary:

  • Fumaric acid has some interesting connections to medicine, but it's not directly used as a medication.
  • Fumaric acid esters are a more relevant form, used in medications like Tecfidera for multiple sclerosis.
  • If you're interested in learning more about fumaric acid or its derivatives for medical purposes, consult a healthcare professional.
Anatomical Therapeutic Chemical Classification
D - Dermatologicals
D05 Antipsoriatics
D05A - Antipsoriatics for topical use
D05AX Other antipsoriatics for topical use
Anatomical Therapeutic Chemical Classification
D - Dermatologicals
D05 Antipsoriatics
D05B - Antipsoriatics for systemic use
D05BX Other antipsoriatics for systemic use
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