Topoisomerase Inhibitor

Topoisomerase Inhibitors are drugs that target a type of enzyme found in cells called topoisomerases. These enzymes are essential for the replication, transcription, and repair of DNA. Topoisomerase inhibitors work by binding to the enzyme and preventing it from carrying out its function. This can cause the DNA to break, which leads to cell death. These drugs are commonly used in cancer treatment, as they can stop cancer cells from replicating and growing. They are also used to treat some bacterial infections, as they can inhibit the growth of the bacteria. Topoisomerase inhibitors are effective against many types of cancer, including leukemia, lung cancer, and ovarian cancer. They can also be used to treat HIV and other diseases caused by viruses.