Thyrotropic
Thyrotropic activity is a term used to describe the ability of a molecule or substance to stimulate or increase the production of thyroid hormones. Thyroid hormones are essential to a variety of metabolic processes, and they play a critical role in controlling the body’s metabolic rate, growth and development, and energy production. Thyrotropic molecules and substances work by binding to the thyroid-stimulating hormone receptor, located on the surface of thyroid cells. This binding stimulates the release of the thyroid hormones thyroxine (T4) and triiodothyronine (T3). The increased levels of thyroid hormones in the blood then stimulate the production and release of other hormones, including growth hormone, cortisol, and insulin. The most common thyrotropic substances are synthetic versions of the thyroid-stimulating hormone (TSH). These synthetic molecules are produced in a laboratory, and they can be used to treat a variety of thyroid disorders. For example, they may be used to treat hypothyroidism, a condition in which the body does not produce enough T4 and T3 hormones. In these cases, the synthetic TSH is used to stimulate the production of more thyroid hormones.