Positive Inotropic

Positive inotropic activity is the ability of a substance to increase the strength of a heart muscle contraction. This can help to improve the heart’s ability to pump blood efficiently and effectively throughout the body. Positive inotropic drugs are often used to treat heart failure, as they help to increase the amount of oxygenated blood being delivered to the body’s organs, thus reducing the symptoms of the condition. Positive inotropic drugs are also used to treat other conditions such as arrhythmias and hypertension. These drugs work by increasing the release of calcium ions from the sarcoplasmic reticulum of the heart muscle cells, which causes the cells to contract more forcefully. This increase in force improves the heart’s ability to pump blood, which can help reduce the symptoms of heart failure.