Goitrogenic

Goitrogenic refers to substances that can interfere with the production of thyroid hormones, resulting in an enlarged thyroid gland, or goiter. Goitrogenic substances can be found in certain foods, such as cruciferous vegetables, soy, and cassava. They can also be found in certain medications and environmental pollutants. Goitrogenic activity can be caused by a variety of mechanisms, including interference with iodine uptake, inhibition of thyroid peroxidase, and inhibition of thyroid hormone synthesis. In some cases, goitrogenic activity can be beneficial, such as in the treatment of hyperthyroidism, but in other cases, it can lead to an enlarged thyroid gland and other side effects.