Corticotrophinogenic
Corticotrophinogenic hormone (CTH) is a hormone produced by the hypothalamus region of the brain, which stimulates the release of hormones from the adrenal cortex. CTH acts on the pituitary gland to release adrenocorticotropic hormone (ACTH). ACTH then works on the adrenal cortex to release glucocorticoids, mineralocorticoids, and androgens. These hormones are essential for the regulation of a wide range of bodily functions. Glucocorticoids are important for stress, energy metabolism, and immune system function. Mineralocorticoids help regulate fluid balance and electrolyte levels. Androgens are important for sexual development and reproductive function. CTH is also involved in the regulation of the hypothalamic-pituitary-adrenal (HPA) axis, which is responsible for the body's response to stress. CTH is also involved in the regulation of appetite and satiety, and can be used to treat conditions such as Cushing's syndrome and Addison's disease.