Bronchorelaxant

Bronchorelaxants are medications used to reduce bronchial spasms in people with asthma, chronic bronchitis, and other respiratory illnesses. These medications work by relaxing the smooth muscles in the walls of the airways, allowing the airways to open up and improve air flow. Bronchorelaxants can be used alone or in combination with other medications, such as bronchodilators and corticosteroids, to make breathing easier. Common bronchorelaxants include muscarinic receptor antagonists, beta-2 agonists, and phosphodiesterase inhibitors. Muscarinic receptor antagonists block the action of the neurotransmitter acetylcholine at the muscarinic receptors, which helps to reduce the spasms in the airways. Beta-2 agonists bind to beta-2 receptors in the airways and cause them to relax, while phosphodiesterase inhibitors prevent the breakdown of cyclic adenosine monophosphate (cAMP), increasing the level of cAMP and also helping to relax the airways.