Anticholestatic

Anticholestatic refers to any drug or other substance that can reduce or counteract the effects of excessive bile secretion, which is known as cholestasis. Cholestasis occurs when the flow of bile from the gallbladder is blocked or impaired, leading to a buildup of bile acids in the liver and other tissues. This can cause significant discomfort and other symptoms, such as jaundice, abdominal pain, nausea, and itching. Anticholestatic drugs work to reduce the amount of bile acids being produced, thereby reducing the symptoms of cholestasis. Common anticholestatic agents include ursodeoxycholic acid, fibrates, statins, and bile acid sequestrants. These drugs are typically used in combination with lifestyle modifications and dietary changes.