12-Lipoxygenase-Inhibitor

12-Lipoxygenase-Inhibitor is a type of drug that works by inhibiting the enzyme 12-Lipoxygenase. This enzyme is involved in the metabolism of arachidonic acid, a fatty acid that is essential for the production of eicosanoids such as prostaglandins, thromboxanes, and leukotrienes. These eicosanoids are involved in a variety of physiological processes, including inflammation and cell death. By inhibiting 12-Lipoxygenase, these drugs reduce the production of eicosanoids, resulting in reduced inflammation and cell death. This makes 12-Lipoxygenase-Inhibitor drugs useful for the treatment of various inflammatory and autoimmune diseases, such as asthma and rheumatoid arthritis.