Kawasaki Disease

Kawasaki disease (also known as Kawasaki syndrome) is a rare, acute, self-limiting vasculitis of unknown etiology. It predominantly affects young children, typically under 5 years of age. It is the leading cause of acquired heart disease in children in the developed world. The disease is characterized by severe inflammation of the blood vessels in the body, especially those in the coronary arteries, leading to aneurysm formation and possible coronary artery stenosis. Symptoms include high fever, rash, lymph node enlargement, and inflammation of the hands, feet, and mouth. Treatment usually involves the administration of intravenous immunoglobulin and aspirin, and may include other medications. The prognosis is usually good if treated early, but there is a risk of coronary artery damage, which can lead to complications such as myocardial infarction and sudden death.