Elephantiasis

Elephantiasis is a condition caused by the nematode worms Wuchereria bancrofti, Brugia malayi, and Brugia timori. It is characterized by extreme swelling, usually of the legs and genitals, due to an accumulation of fluids in the tissues. In addition, the skin can become thick, dry, and scaly. Elephantiasis is a form of lymphedema, a condition in which the lymphatic system fails to adequately drain fluid from the tissues. It is most commonly found in tropical and subtropical regions where the worms are most common. In severe cases, the condition can lead to disability. Treatment may include the use of antibiotics, antifilarial medications, and lymphatic drainage massage. Surgery may be necessary in some cases.