Liranaftate

Liranaftate is an antifungal medication used to treat various fungal skin infections, such as athlete's foot, jock itch, ringworm, and tinea versicolor. It is available in topical cream, gel, and solution forms. It works by killing the fungi that cause the infection. Common side effects include burning, itching, and redness.

Liranaftate is a topical antifungal medication used to treat fungal skin infections. Here's a breakdown of its key points:

• Conditions treated: It targets tinea infections, which include athlete's foot (tinea pedis), ringworm (tinea corporis), and jock itch (tinea cruris).
• Brand name: Zefnart (approved for use in Japan only)
• How it works: Liranaftate acts as a squalene epoxidase inhibitor. This means it disrupts the fungus's ability to produce ergosterol, a vital component of its cell membrane. Without proper cell membrane function, the fungus dies.
• Dosage: It comes as a 2% cream applied topically to the affected area.

Additional information:

• Liranaftate was approved in Japan in 2000. There's no information on if or when it might be available elsewhere.
• While not as common, other names for liranaftate include piritetrate and M-732.