Introduction
Dipivefrine is a medication used to treat glaucoma and ocular hypertension. It is a prodrug of epinephrine and works by increasing the outflow of aqueous humor from the eye. It is usually administered as eyedrops, although it may also be given as an injection. Side effects may include irritation, redness, and increased intraocular pressure.
Dipivefrin, also sold under the brand name Propine among others, is a medication used to treat glaucoma . It is a prodrug of epinephrine, meaning it needs to be converted into another substance (epinephrine) to have its effect.
Dipivefrin is specifically used to lower pressure inside the eye in people with open-angle glaucoma. It comes as an ophthalmic solution (eye drops) that is typically applied every 12 hours.
Here's how dipivefrin works:
- Penetrates the cornea: Dipivefrin has a special property that allows it to pass through the cornea, the clear dome at the front of the eye.
- Converted to epinephrine: Once inside the eye, enzymes convert dipivefrin into epinephrine.
- Reduces fluid production: Epinephrine then works by reducing the production of fluid within the eye.
- Increases fluid outflow: It also increases the outflow of fluid from the eye.
By reducing fluid production and increasing outflow, dipivefrin helps lower pressure inside the eye, which is important for preventing glaucoma-related vision loss.
Important points to remember about Dipivefrin:
- It is not a cure for glaucoma, but it can help control the condition.
- It may not be suitable for everyone, and it's crucial to talk to your doctor about any potential side effects or interactions with other medications you are taking.
- Dipivefrin is not currently available in the United States.