Dimethoxanate is a cough suppressant. It is an oral sulfonamide antibiotic used to treat bacterial infections. It works by stopping the growth of bacteria. It is commonly used to treat respiratory tract infections, urinary tract infections, and skin infections. It may also be used to prevent certain bacterial infections. Common side effects include nausea, vomiting, diarrhea, and rash.
Dimethoxanate is a cough suppressant that belongs to the phenothiazine class of medications. Phenothiazines are a group of drugs with a wide range of effects, including antipsychotic, antiemetic (antiemetic medications help prevent nausea and vomiting), and antihistaminic effects. Dimethoxanate works by blocking the cough reflex at the level of the brainstem.
Dimethoxanate was introduced in Europe in the early 1900s, but it was never approved for marketing in the United States by the Food and Drug Administration (FDA) due to a lack of evidence of efficacy. In 1975, the FDA withdrew its approval for marketing dimethoxanate in the US.
Some common trade names for dimethoxanate include Cothera, Cotrane, Atuss, Perlatoss, and Tossizid. These medications are no longer available in the US.