Dactinomycin, also known as actinomycin D, is an antineoplastic antibiotic derived from Streptomyces parvullus. It is used to treat Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, and other childhood cancers. It works by interfering with the transcription of genetic material, inhibiting the growth of cancer cells. Dactinomycin is usually administered intravenously or intramuscularly. Side effects include nausea, vomiting, hair loss, anemia, low white blood cell counts, and an increased risk of infection.
Dactinomycin, also known as actinomycin D, is a chemotherapy medication used to treat a number of types of cancer . This includes Wilms tumor, rhabdomyosarcoma, Ewing's sarcoma, trophoblastic neoplasm, testicular cancer, and certain types of ovarian cancer. It is given by injection into a vein [2].
Dactinomycin works by damaging the cancer cells' DNA. When DNA is damaged, a cell cannot divide into 2 new cells, so it helps to stop the cancer growing [6].