Carbetocin

Carbetocin is a synthetic peptide analogue of oxytocin, a naturally occurring hormone in the body that helps regulate the uterus during labor. It is used to prevent or reduce bleeding after childbirth. Carbetocin works by stimulating the uterus to contract and clamp down on any remaining blood vessels in the area, reducing the amount of blood loss. It is used intravenously and is typically administered just after delivery of the placenta. It is usually given as a single dose, but may be repeated if needed. Side effects of Carbetocin may include nausea, vomiting, and headaches.

Carbetocin is a medication used to prevent excessive bleeding after childbirth, particularly following a cesarean section . It works similarly to oxytocin,

  • Function: Helps prevent excessive bleeding after childbirth by stimulating the uterus to contract.
  • Dosage: Given as a single injection into a vein or muscle.
  • Effectiveness: Appears to be as effective as oxytocin in preventing postpartum hemorrhage.
  • Advantages:
    • Requires only one dose, unlike oxytocin which may need to be given as a continuous infusion.
    • Stable at room temperature, unlike oxytocin which needs to be refrigerated. This can be especially beneficial in settings with limited access to refrigeration.
Anatomical Therapeutic Chemical Classification
H - Systemic hormonal preparations, excluding sex hormones and insulins
H01 Pituitary and hypothalamic hormones and analogues
H01B - Posterior pituitary lobe hormones
H01BB Oxytocin and analogues
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