Broxyquinoline is an antimalarial drug used to treat certain types of malaria. It is usually given as a combination with other drugs, such as atovaquone/proguanil. It works by preventing the parasites from growing and multiplying in the body. It is used to treat both chloroquine-sensitive and resistant forms of malaria. Common side effects of this medication include nausea, vomiting, diarrhea, and abdominal pain.
Broxyquinoline, also known by the brand name Entero-Vioform, was previously used as a prescription medication to treat amoebic dysentery, a type of intestinal infection caused by the parasite Entamoeba histolytica. However, it is no longer recommended for this purpose due to safety concerns.
Here's a summary of Broxyquinoline's past and present use:
Past use:
- Antiprotozoal medication: Broxyquinoline was used to treat amoebic dysentery by killing the parasite causing the infection.
- Available as tablets and topical cream: It was available in both oral and topical forms for treating intestinal and external infections, respectively.
Reasons for discontinuation:
- Neurological side effects: Broxyquinoline was linked to a rare but severe neurological disorder called subacute myelo-optic neuropathy (SMON), causing vision problems, numbness, and weakness in the arms and legs.
- Availability of safer alternatives: Other medications with fewer side effects have become the preferred treatment for amoebic dysentery.
Current status:
- Not recommended for use: Due to the potential for serious side effects, Broxyquinoline is no longer recommended for any medical use.
- Banned in various countries: The medication has been banned in several countries, including the United States and the European Union.
Important points to remember:
- Do not use Broxyquinoline under any circumstances.
- Consult a healthcare professional for diagnosis and treatment of any suspected amoebic dysentery or other medical conditions.
- There are safe and effective alternative medications available for treating amoebic dysentery and other intestinal infections.
If you encounter any information suggesting Broxyquinoline as a treatment option, it is crucial to disregard such advice and seek guidance from a qualified medical professional.