Zinc acetate

International Numbering System (INS) for Food Additives: 650

Food additives Europe numbers: E650 

Zinc acetate is a chemical compound used as a dietary supplement and as a medication. It is a salt composed of zinc and acetic acid, and it is available in both oral and topical forms. As a dietary supplement, zinc acetate is used to prevent and treat zinc deficiencies. It may also be used to treat Wilson's disease, a rare inherited disorder that causes copper to accumulate in the body. As a topical medication, zinc acetate is used to treat skin conditions such as acne, cold sores, and psoriasis.

Zinc acetate is a substance that combines zinc, an essential mineral, with acetic acid, commonly known as vinegar. It has various applications, including medical uses:

Medical Uses:

  • Treatment for Wilson's Disease: This is the primary medicinal use of zinc acetate. Wilson's disease is a rare genetic disorder causing excess copper buildup in the body, particularly in the liver and brain. Zinc acetate helps manage this condition by:
    • Inducing the production of a protein in the intestines that binds copper, preventing its absorption from food.
    • Promoting copper excretion through urine.
  • Nutritional Supplement: In some cases, zinc acetate might be used as a dietary supplement to address zinc deficiency. Zinc deficiency can occur due to inadequate dietary intake, certain medical conditions, or chronic illnesses.

Other Uses:

  • Astringent: In low concentrations, zinc acetate has astringent properties. Astringents cause tissues to contract and can help dry out minor cuts or wounds.
  • Antimicrobial Effects: Zinc acetate might possess mild antibacterial properties similar to zinc sulfate.

Administration:

  • Zinc acetate is typically administered orally in capsule form.
  • For Wilson's disease treatment, it's usually taken three times a day on an empty stomach (at least an hour before or two hours after meals) to optimize copper absorption reduction.
Anatomical Therapeutic Chemical Classification
A - Alimentary tract and metabolism
A16 Other alimentary tract and metabolism products
A16A - Other alimentary tract and metabolism products
QA16AX Various alimentary tract and metabolism products
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