Vidarabine (also known as adenine arabinoside) is an antiviral medication that is used to treat herpes simplex virus infections, such as chickenpox and herpes zoster (shingles). It works by blocking the activity of the virus in the body. It is usually given by injection into a vein. Common side effects include nausea, rash, and fever.
Vidarabine is an antiviral medication primarily used to treat infections caused by specific viruses [1, 2]. Here's a closer look at its key characteristics:
What it is:
- An antiviral medication with activity against certain viruses [1].
- Available in topical (ointment) and injectable forms [1].
What it's used for:
- Treats herpes simplex virus (HSV) infections of the eye, including keratitis (corneal inflammation) caused by HSV-1 and HSV-2 [1, 2].
- In some cases, it may be used for herpes zoster (shingles) in immunocompromised patients, like those with AIDS [2].
How it works:
- Interferes with the virus's ability to replicate and spread within the body [2].
How it's used:
- Topical form (ointment) is applied directly to the affected eye, typically several times a day [1].
- Injectable form is administered by a healthcare professional [1].
Potential side effects:
- Topical form: stinging, burning, eye irritation [1].
- Injectable form: nausea, vomiting, bone marrow suppression [1].
Important considerations:
- Vidarabine is not a cure for viral infections, but it can help shorten the duration and severity of symptoms [2].
- There can be resistance to Vidarabine, so it's crucial for doctors to monitor its effectiveness [2].
- Vidarabine may interact with other medications, so it's important to inform your doctor about all medications you're taking [1].
Anatomical Therapeutic Chemical Classification
J - Antiinfectives for systemic use
J05 Antivirals for systemic use
J05A - Direct acting antiviral drugs
J05AB Nucleosides and nucleotides excluding reverse transcriptase inhibitors
ATC Code
Anatomical Therapeutic Chemical Classification
S - Sensory organs
S01 Ophthalmologicals
S01A - Anti-infectives
S01AD Antivirals
ATC Code
External Links
Vidarabine