Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally occurring bile acid found in some species of bears. It is used as a medication to treat liver diseases such as primary biliary cirrhosis (PBC), primary sclerosing cholangitis (PSC), and cholestatic liver diseases. UDCA is usually taken orally in the form of tablets or capsules. It works by decreasing the amount of cholesterol released from the liver and decreasing the absorption of cholesterol from the gut. It also helps to thin bile, making it easier for the liver to clear it from the body. UDCA can help to reduce symptoms of liver disease and slow the progression of the disease.
Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally occurring bile acid found in small amounts in human bile. It is also available as a prescription medication used to dissolve cholesterol gallstones and treat certain liver diseases.
- Function: UDCA helps with digestion by breaking down fats in the small intestine.
- Medical uses:
- Dissolving cholesterol gallstones
- Primary biliary cirrhosis (PBC), a progressive autoimmune disease of the bile ducts in the liver
- Nonalcoholic fatty liver disease (NAFLD)
- Mechanism of action: UDCA works by lowering the amount of cholesterol in bile, which can help to dissolve gallstones. It also has anti-inflammatory and antioxidant effects, which may be helpful in treating PBC.
- Dosage: The dosage of UDCA will vary depending on the condition being treated.
- Side effects: UDCA is generally well-tolerated, but some people may experience mild side effects such as diarrhea, abdominal pain, or fatigue.