Trimetazidine

Trimetazidine is a medication used to treat angina (chest pain) caused by coronary artery disease. It works by reducing the amount of fatty acids in the body and improving the efficiency of the heart. This medicine is available as an oral tablet, sustained release tablet, and injection. Trimetazidine is not recommended for use in people with heart failure or other heart problems. Common side effects include dizziness, headache, nausea, and diarrhea.

Trimetazidine is a medication used to treat angina pectoris, which is chest pain caused by reduced blood flow to the heart. Here's a closer look at how it works and its uses:

Function:

  • Mechanism: Trimetazidine's exact mechanism of action is not fully understood, but it's believed to work in a couple of ways:
    • Metabolic Shift: It inhibits the breakdown of fatty acids for energy production in heart cells. This encourages the use of glucose instead, which requires less oxygen for the heart to utilize.
    • Cellular Protection: It might also have some protective effects on heart cells during oxygen-deprived states.

Applications:

  • Angina Pectoris: Trimetazidine is primarily used to manage angina symptoms, particularly in cases where other first-line medications are not effective or tolerated well. It can help reduce the frequency and severity of chest pain episodes.
Anatomical Therapeutic Chemical Classification
C - Cardiovascular system
C01 Cardiac therapy
C01E - Other cardiac preparations
C01EB Other cardiac preparations
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