Trichloroethylene

Trichloroethylene is a solvent used in a variety of industrial and commercial applications, including dry cleaning, metal degreasing, and adhesives. It is also used medically as a sedative and anesthetic. Trichloroethylene is a colorless liquid with a sweet smell. It is flammable and exposure can lead to irritation of the eyes, skin, and upper respiratory tract. Long-term exposure to trichloroethylene is linked to an increased risk of cancer and other health effects.

Trichloroethylene (TCE) is not a currently recommended medical substance. While it has a history of use in medicine, it's no longer considered safe due to health risks. Here's a breakdown of TCE:

Historical Medical Use:

  • Trichloroethylene was once used as a general inhalational anesthetic, particularly during childbirth and for trigeminal neuralgia (severe facial pain) in the past.
  • This use has been discontinued due to the availability of safer alternatives and the discovery of its hazardous properties.

Health Risks:

  • TCE is classified as a known carcinogen (cancer-causing agent) by multiple agencies.
  • Exposure to TCE has been linked to various health problems, including:
    • Kidney cancer
    • Liver cancer
    • Non-Hodgkin's lymphoma
    • Central nervous system depression (dizziness, headache, confusion)
    • Respiratory irritation
    • Birth defects (with long-term maternal exposure)

Current Status:

  • TCE is primarily used as an industrial solvent for degreasing metals and in refrigerants.
  • Regulations limit occupational exposure due to its health risks.
  • TCE exposure can also occur through contaminated drinking water sources.
Anatomical Therapeutic Chemical Classification
N - Nervous system
N01 Anesthetics
N01A - Anesthetics, general
N01AB Halogenated hydrocarbons
External Links