Trichlorfon (DEP) is a low-toxic organophosphorous insecticide developed by Bayer AG (Germany). It is converted into dichlorvos within plant body and thermally decomposed into dichlorvos and dimethyl phosphate (DMP).
Trichlorfon dimethyl (RS)-2,2,2-trichloro-1-hydroxyethylphosphonate
Trichlorfon, also known as metrifonate, is an insecticide that was formerly used in medicine to treat schistosomiasis, a parasitic disease caused by blood flukes. It is no longer commonly used for this purpose due to the availability of safer and more effective medications. Trichlorfon is an organophosphate, a class of chemicals that can be toxic to humans if not handled properly.
Trichlorfon works by inhibiting cholinesterase, an enzyme that is essential for the proper functioning of the nervous system. Inhibition of cholinesterase can lead to a variety of symptoms, including nausea, vomiting, diarrhea, dizziness, weakness, and respiratory paralysis. In severe cases, trichlorfon poisoning can be fatal.
Trichlorfon is a restricted-use pesticide in many countries, meaning that it can only be used by certified applicators. It is important to follow all safety precautions when handling trichlorfon, including wearing gloves, protective clothing, and a respirator.