Tilbroquinol (brand name Tilcotil) is a nonsteroidal anti-inflammatory drug (NSAID) used to treat inflammation and pain. It is typically used to treat mild to moderate pain, such as that associated with muscle sprains, strains, and arthritis. It is also used in the treatment of fever and to reduce swelling. Tilbroquinol works by blocking the production of certain chemicals in the body that cause inflammation and pain. Side effects may include nausea, vomiting, stomach pain, and diarrhea.
Tilbroquinol is a medication that was once used to treat amoebiasis, an infection caused by the parasite Entamoeba histolytica. It was also used against Vibrio cholerae, the bacterium that causes cholera. However, it has been withdrawn from the market in some countries, including France and Saudi Arabia, due to the risk of serious liver damage.
Tilbroquinol is an 8-hydroxyquinoline compound, which means it belongs to a class of drugs that work by killing parasites. The exact way that tilbroquinol works is not fully understood, but it is thought to work by interfering with the parasite's ability to produce DNA.
Tilbroquinol was typically taken as a capsule by mouth. The usual dosage was 400 milligrams (mg) twice a day for up to 10 days.
Tilbroquinol can cause a number of side effects, including:
- Nausea
- Vomiting
- Diarrhea
- Abdominal pain
- Headache
- Dizziness
- Skin rash
In some cases, tilbroquinol can also cause more serious side effects, such as liver damage. Because of this risk, tilbroquinol is no longer recommended for use in many countries.