Tasosartan is a prescription medication used to treat high blood pressure (hypertension). It belongs to a class of drugs called angiotensin II receptor blockers (ARBs), which work by blocking the action of a hormone in your body that causes blood vessels to narrow. This helps to relax the blood vessels and lower your blood pressure. Tasosartan may also be used to treat other conditions as determined by your doctor. It was withdrawn from FDA review by the manufacturer after phase III clinical trials showed elevated transaminases (a sign of possible liver toxicity) in a significant number of participants given the drug
Tasosartan was a medication designed to be an angiotensin II receptor blocker (ARB) for treating high blood pressure (essential hypertension) [1, 2]. However, it was never approved for medical use [1].
Here's some key information about Tasosartan:
- Function: It aimed to block the angiotensin II receptor, which would cause blood vessels to relax and lower blood pressure [2].
- Status: Development of Tasosartan was discontinued after phase III clinical trials showed that a concerning number of participants experienced elevated liver enzymes in their blood [1]. It is not available anywhere in the world.