Talazoparib is a PARP inhibitor that is used to treat certain types of advanced breast cancer. It works by blocking an enzyme called PARP that helps cancer cells repair themselves, which can stop cancer cells from growing. Talazoparib is usually taken as a pill once a day. Common side effects include nausea, fatigue, and low red blood cell count.
Talazoparib is a medication sold under the brand name Talzenna. It is an anti-cancer medication used for the treatment of breast cancer and prostate cancer. It belongs to a class of drugs called poly (ADP-ribose) polymerase (PARP) inhibitors Wikipedia: en.wikipedia.org/wiki/Talazoparib. PARP is an enzyme involved in the repair of DNA damage. By inhibiting PARP, talazoparib can cause cancer cells to die.
Talazoparib is typically used to treat breast cancer that has spread to other parts of the body (metastatic breast cancer) in women who have a certain genetic mutation (BRCA mutation). It can also be used in combination with another medication (enzalutamide) to treat metastatic castration-resistant prostate cancer in men who have a certain genetic mutation (HRR mutation).
Here are some additional details about Talazoparib:
- Dosage and administration: Talazoparib is taken orally, once a day, with or without food.
- Side effects: Common side effects of talazoparib include anemia, fatigue, nausea, vomiting, diarrhea, and headache. Talazoparib can also increase the risk of certain serious side effects, such as myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML).
- Warnings and precautions: Talazoparib can interact with other medications. It is important to tell your doctor about all the medications you are taking, including prescription and over-the-counter medications, vitamins, and herbal supplements. Talazoparib can also cause birth defects. Women who are pregnant or breastfeeding should not take talazoparib.