International Numbering System (INS) for Food Additives: 325
Food additives Europe numbers: E325
Functional Category
Antimicrobial preservative; buffering agent; emulsifying agent; flavoring agent; humectant.
Applications in Pharmaceutical Formulation
Sodium lactate is widely used in cosmetics,(1,2) food products and pharmaceutical applications including parenteral and topical formulations. Therapeutically, sodium lactate is used in infusions as a component of Ringer-lactate solution; as an alternative for sodium hydrogencarbonate in light acidosis; as a rehydrating agent; and as a carrier for electrolyte concentrates or medicines in perfusion/ infusion solutions.
Description
Sodium lactate occurs as a clear, colorless, slightly syrupy liquid. It is odorless, or has a slight odor with a characteristic saline taste. It is hygroscopic.
Stability and Storage Conditions
Sodium lactate should be stored in a well-closed container in a cool, dry, place. Sodium lactate is combustible and decomposes upon heating.
Incompatibilities
See Lactic Acid.
Safety
Sodium lactate occurs naturally in the body and is involved in physiological processes. It is generally regarded as a relatively nontoxic and nonirritant material when used as an excipient. Low concentrations are well tolerated by skin and eye mucosa, although higher concentrations should be avoided. LD50 (rat, IP): 2 g/kg(3)