Roxatidine acetate is an H2 receptor antagonist used to treat gastroesophageal reflux disease (GERD). It is also used to treat peptic ulcers, erosive esophagitis, and other conditions related to excess stomach acid production. Roxatidine acetate works by blocking the action of the histamine-2 receptors in the stomach, reducing the amount of acid that is produced. It is taken orally, usually once or twice a day. Common side effects may include headache, diarrhea, and nausea.
Roxatidine acetate is a medication used to treat conditions related to excess stomach acid production [1]. Here's a breakdown of its key points:
Function:
- H2-receptor antagonist: It belongs to a class of drugs that block histamine receptors in the stomach. Histamine is a chemical that stimulates the stomach to produce acid. By blocking these receptors, roxatidine acetate reduces the amount of acid produced [2].
Conditions it treats:
- Peptic ulcers: These are sores in the lining of the stomach or duodenum (first part of the small intestine) caused by stomach acid [1].
- Zollinger-Ellison syndrome: This is a rare condition that causes the stomach to produce too much acid [1].
- Erosive esophagitis: This is inflammation of the esophagus (the tube that connects the mouth to the stomach) caused by stomach acid backing up from the stomach [1].
- Gastroesophageal reflux disease (GERD): This is a condition in which stomach acid flows back up into the esophagus, causing heartburn and other symptoms [1].
- Gastritis: This is inflammation of the lining of the stomach [1].
Availability:
- Roxatidine acetate is currently approved for medical use in some countries, including South Africa under the brand name Roxit [3]. It's important to note that it may not be available everywhere.
Administration:
- It is typically taken orally as a tablet [1].
Things to remember:
- Consult a doctor: Roxatidine acetate is a prescription medication and should only be taken under the supervision of a doctor [1].
- Alternatives: There are other medications available to treat these conditions, so your doctor will determine if roxatidine acetate is the right choice for you.
Anatomical Therapeutic Chemical Classification
A - Alimentary tract and metabolism
A02 Drugs for acid related disorders
A02B Drugs for peptic ulcer and gastro-oesophageal reflux disease (GORD)
A02BA H2-receptor antagonists
ATC Code
External Links
Roxatidine acetate