Reslizumab is a monoclonal antibody (mAb) used to treat severe asthma. It is an interleukin-5 (IL-5) antagonist that helps reduce the number of eosinophils, a type of white blood cell in the body that can lead to asthma symptoms. It is given as an intravenous (IV) infusion to adults and children 12 years of age and older who are taking other asthma medications but still have frequent asthma attacks. Reslizumab is thought to reduce inflammation that is associated with asthma, which can help prevent asthma attacks.
Reslizumab is a prescription medication used to treat a specific type of chronic inflammatory airway disease called eosinophilic asthma. Here's a closer look at its mechanism of action and how it helps with this condition:
How it Works:
- Reslizumab belongs to a class of drugs called interleukin-5 (IL-5) antagonists [1, 2]. These medications target a specific protein called interleukin-5, which plays a crucial role in the development and survival of eosinophils [1, 2].
- Eosinophils are a type of white blood cell that contribute to allergic inflammation in asthma. By blocking IL-5, Reslizumab helps to decrease the number of eosinophils in the airways, reducing inflammation and improving airflow [1, 2].
How it's Administered:
- Reslizumab is administered by intravenous (IV) infusion, typically every 4 or 8 weeks, depending on the prescribed dose [1, 2]. A healthcare professional will administer the medication in a clinic setting.
Benefits of Reslizumab:
- In patients with eosinophilic asthma, Reslizumab can help to:
- Reduce asthma flare-ups (attacks) [1, 2].
- Improve lung function [1, 2].
- Decrease the need for oral steroid medications often used for asthma control [1, 2].
Important Considerations:
- Reslizumab is not suitable for everyone. Your doctor will assess your individual situation and medical history before prescribing it [2].
- It's important to note that Reslizumab is not a cure for asthma, but it can help manage the condition [2].
- Potential side effects include headache, upper respiratory tract infection, and injection site reactions [2].
- Regular doctor visits and monitoring are necessary while taking Reslizumab [2].