Propoxyphene napsylate is a substance that used to be prescribed as a pain reliever. It belonged to a class of drugs called opioids. However, the U.S. Food and Drug Administration (FDA) recommended against its use in 2010 due to the risk of serious heart problems, even at recommended doses. Propoxyphene napsylate is no longer available in the market.
Here's some additional information about propoxyphene napsylate:
- What it was used for: Propoxyphene napsylate was used to relieve mild to moderate pain. It was sometimes combined with acetaminophen (a different pain reliever) in a medication called Darvocet.
- How it worked: Propoxyphene napsylate worked by attaching to opioid receptors in the brain and spinal cord. This blocked pain signals from being sent to the brain.
- Risks: As mentioned earlier, propoxyphene napsylate can cause serious heart problems, including irregular heartbeat and QT prolongation (a condition that can increase the risk of sudden death). It can also be addictive and lead to dependence.