Pipazetate or pipazethate (USAN), is a pyridobenzthiazine cough suppressant, closely related to the phenothiazine class. Pipazetate is a prescription medication used to treat depression and anxiety in adults. It works by blocking the reuptake of certain neurotransmitters in the brain, such as norepinephrine, which helps to improve mood. Common side effects of Pipazetate include dry mouth, constipation, and drowsiness.
Pipazethate is a medication that was previously marketed as a cough suppressant. It is a non-narcotic medication, meaning it does not depress the central nervous system. Pipazethate was withdrawn from the market due to safety concerns, as it can cause seizures at high doses.
How it works to suppress coughs is not fully understood, but it is believed to work by affecting certain receptors in the brain and throat. It also has local anesthetic properties.
Pipazethate is no longer a recommended medication for coughs. There are other safer and more effective cough suppressants available.