Perhexiline

Perhexiline is a prescription medicine used to treat angina (chest pain). It is also used to help prevent or reduce the severity of angina attacks. Perhexiline belongs to a group of drugs called anti-anginal agents. It works by increasing the blood supply to the heart muscle and decreasing the heart's workload. This helps to reduce the frequency and severity of angina attacks. Common side effects of perhexiline include nausea, dizziness, headache, and fatigue.

Perhexiline is a medication used to manage angina pectoris, specifically:

  • Type of angina: Reduces frequency of moderate to severe angina attacks, which is chest pain caused by reduced blood flow to the heart.
  • Mechanism of action: It's classified as a coronary vasodilator, although the exact way it works isn't fully understood. It's believed to influence how the heart uses fuel and oxygen, potentially improving efficiency.

Here's a breakdown of key points about perhexiline:

  • Short-term or long-term use: Perhexiline can be used for short-term (less than 3 months) therapy before bypass surgery or other procedures to improve blood flow. In some cases, it might be used for long-term management of angina symptoms if other medications haven't been effective.
  • Important considerations:
    • Perhexiline can cause side effects like neuropathy (nerve damage) and hepatitis (liver inflammation). Regular monitoring by a doctor is crucial.
    • It's not a first-line treatment and is typically reserved for situations where other medications haven't provided adequate relief.
Anatomical Therapeutic Chemical Classification
C - Cardiovascular system
C08 Calcium channel blockers
C08E - Non-selective calcium channel blockers
C08EX Other non-selective calcium channel blockers
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