Penamecillin, an acetoxymethyl ester of benzylpenicillin, is a prodrug processed to benzylpenicillin by esterases.
Penamecillin is a prodrug, meaning it's an inactive medication that needs to be processed by the body to become active. In the case of penamecillin, it is converted into benzylpenicillin, a type of penicillin antibiotic, by esterases which are enzymes found throughout the body but concentrated in the liver and blood plasma [1]. Benzylpenicillin is effective against a variety of bacteria that can cause infections.
Penamecillin is typically used to treat mild to moderate infections such as:
- Pneumonia
- Skin infections
- Ear infections
- Throat infections
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Penamecillin