Mexiletine

Mexiletine is an oral medication used to treat irregular heartbeats, such as atrial fibrillation and ventricular tachycardia. It is also used to treat chronic pain. It belongs to a class of drugs called antiarrhythmics. It works by blocking sodium channels in the heart, which helps to regulate the electrical signals that control the heart rate. Mexiletine is usually taken twice daily, with or without food. Possible side effects include nausea, dizziness, headache, and fatigue.

Mexiletine is a prescription medication used primarily to treat a specific heart condition:

  • Ventricular arrhythmias: These are irregular heartbeats that originate in the ventricles, the lower chambers of the heart. Ventricular arrhythmias can be serious and potentially life-threatening.

How Mexiletine Works:

The exact mechanism of Mexiletine's action is not fully understood, but it's believed to work by:

  • Sodium channel blocking: Mexiletine affects the electrical activity in the heart by blocking sodium channels in heart muscle cells. This helps to stabilize the heart's rhythm and reduce the occurrence of irregular heartbeats.

Applications:

Mexiletine is primarily used to treat ventricular arrhythmias after a doctor has determined they are not caused by a different underlying condition.

  • It may also be used in some cases to treat chronic pain, although this is a less common application.

Dosage and Forms:

  • Mexiletine comes in capsule form and is taken orally, usually with or without food.
  • The dosage will be determined by your doctor based on your individual needs and factors like your weight, kidney function, and other medications you're taking.

Important Considerations:

  • Mexiletine can interact with other medications, so inform your doctor about all medications and supplements you're taking before starting it.
  • Common side effects of Mexiletine include tremor, dizziness, lightheadedness, nausea, and vomiting.
  • Mexiletine can also worsen some heart rhythm problems in rare cases. It's crucial to be monitored by your doctor while taking this medication.
Anatomical Therapeutic Chemical Classification
C - Cardiovascular system
C01 Cardiac therapy
C01B - Antiarrhythmics, class I and III
C01BB Antiarrhythmics, class Ib
External Links