Meterleptin (Metreleptin) is a recombinant form of the hormone leptin, a protein that is produced in the body and which is involved in appetite control and energy balance. Meterleptin is used to treat lipodystrophy, a rare disorder characterized by an abnormal distribution of body fat and a lack of fat on the face, arms, and legs. Meterleptin helps to restore healthy levels of fat and is usually used along with lifestyle changes such as a healthy diet and exercise. Side effects may include increased appetite, increased weight, nausea, and diarrhea.
Metreleptin is a man-made version of the hormone leptin. Leptin is a hormone produced by fat cells that helps regulate appetite and body weight. Metreleptin is sold under the brand name Myalept, among others.
Metreleptin is a prescription drug used to treat complications of leptin deficiency in people with lipodystrophy. Lipodystrophy is a group of rare diseases that cause a loss of fat tissue from the body. There are different types of lipodystrophy, and they can cause a variety of symptoms, including:
- High triglycerides (a type of fat in the blood)
- Low HDL cholesterol ("good" cholesterol)
- High blood sugar
- Fatty liver disease
- Diabetes
- Liver problems
- Heart problems
Metreleptin is given as an injection under the skin (subcutaneous). The usual dose is based on the patient's weight. Metreleptin can cause side effects, including injection site reactions, headache, fatigue, nausea, vomiting, and diarrhea.