Mesalazine (also known as mesalamine or 5-aminosalicylic acid) is an anti-inflammatory drug used to treat inflammatory bowel diseases such as ulcerative colitis, Crohn’s disease, and proctitis. It works by decreasing inflammation in the intestines and reducing the production of certain chemicals that cause inflammation. It is also used to reduce the risk of colorectal cancer in people with ulcerative colitis.
Mesalazine, also known as mesalamine or 5-aminosalicylic acid (5-ASA), is a medication used to treat inflammatory bowel disease (IBD), including:
- Ulcerative colitis: This is an inflammatory bowel disease that affects the inner lining of the colon (large intestine).
- Crohn's disease: This is another inflammatory bowel disease that can affect any part of the digestive tract, from the mouth to the anus. Mesalazine is typically used for mild to moderate Crohn's disease.
Here's a breakdown of how Mesalazine works and what to know about it:
How it works:
- The exact mechanism of how Mesalazine works is not fully understood, but it's believed to act by reducing inflammation in the gut.
- It's thought to work by stopping the body from producing chemicals that cause inflammation in the intestine.
- This helps to improve symptoms like diarrhea, rectal bleeding, and abdominal pain.
Dosage and forms:
- Mesalazine comes in various forms, including tablets, granules, rectal suppositories, enemas, and foam.
- The doctor will determine the right form, dosage, and frequency based on the severity of your condition and whether you're treating a flare-up or aiming to maintain remission.
Important points to remember:
- Mesalazine is typically only available by prescription.
- It may take some time, up to a few weeks, for Mesalazine to show its full effects.
- Common side effects include headache, nausea, abdominal pain, and diarrhea.
- Mesalazine can interact with other medications, so be sure to tell your doctor about all the medications you are taking.
Anatomical Therapeutic Chemical Classification
A - Alimentary tract and metabolism
A07 Antidiarrheals, intestinal anti-inflammatory/anti-infective agents
A07E - Intestinal anti-inflammatory agents
A07EC Aminosalicylic acid and similar agents
ATC Code
External Links
Mesalazine