Maraviroc

Maraviroc is an antiviral medication used to treat HIV infection. It works by blocking the virus from entering and infecting cells. It is usually prescribed along with other HIV medications as part of a combination therapy. Maraviroc is available in tablet form and is taken twice daily with or without food. Common side effects include headache, nausea, fatigue, and diarrhea.

Maraviroc, sold under the brand names Selzentry (US) and Celsentri (outside US), is a prescription medication used to treat a specific type of HIV infection. Here's a breakdown of its key points:

What it's used for:

  • Treats a certain type of Human Immunodeficiency Virus (HIV) infection in adults and children (weighing at least 4.4 lbs or 2 kg).
  • Important to note: It's specifically effective against strains of HIV that use a specific receptor called CCR5 to enter cells (CCR5-tropic HIV-1). Maraviroc is not effective against strains that use a different receptor (CXCR4) or both receptors.

How it works:

  • Belongs to a class of drugs called HIV entry inhibitors.
  • Works by blocking the CCR5 receptor on the surface of immune system cells (T-cells). This prevents the HIV virus from attaching to and entering these cells, thereby slowing down the spread of the virus in the body.

Effectiveness:

  • Maraviroc is used in combination with other antiretroviral medications to help manage HIV infection.
  • It helps decrease the amount of HIV in the blood, which can improve immune function and reduce the risk of complications from HIV.

Important Safety Information:

  • Maraviroc is not a cure for HIV infection and does not prevent transmission of the virus to others.
  • It can have side effects, including headache, fatigue, diarrhea, and liver problems.
  • There are also potential drug interactions, so it's crucial to inform your doctor about all medications you take before starting Maraviroc.
     
Anatomical Therapeutic Chemical Classification
J - Antiinfectives for systemic use
J05 Antivirals for systemic use
J05A - Direct acting antiviral drugs
J05AX Other antivirals
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