International Numbering System (INS) for Food Additives: 464
Hypromellose, also known as hydroxypropyl methylcellulose (HPMC), is a semi-synthetic, inert, viscoelastic polymer used as an ophthalmic lubricant, an excipient and a suspending and emulsifying agent in pharmaceuticals. It is a non-ionic, water-soluble polymer, derived from cellulose. Hypromellose is used in a variety of ophthalmic products including ointments, gels, and drops to treat dry eye, to protect the surface of the eye, and to act as a lubricant. It is also used in a wide range of oral and topical formulations, including tablets, capsules, creams, lotions, and suppositories.
Hydroxy propyl methyl cellulose
Hydroxypropyl methylcellulose (HPMC), also known by the trade name hypromellose, is a semisynthetic, inert, viscoelastic polymer commonly used in various medical applications .
Here's a breakdown of its properties:
- Chemical type: Semisynthetic polymer, a modified version of cellulose, a natural substance found in plants
- Properties: Odorless, tasteless, white to slightly off-white powder, soluble in water
- Uses in medicine:
- Eye drops: Lubricates and protects the eye, relieves dry eye symptoms
- Oral medications: Binds ingredients together, controls the release of medication in the body
HPMC is generally considered safe for most people. It is non-toxic and doesn't irritate the skin or eyes. In rare cases, oral ingestion may cause mild stomach upset or bloating.