Flunarizine is a medication used to prevent migraine headaches and to treat vertigo (a condition that causes dizziness). It works by blocking certain receptors in the brain, which helps to reduce the frequency of migraine attacks and helps to reduce vertigo symptoms. It also affects certain chemicals in the brain, which can help to reduce anxiety. Flunarizine is generally taken orally once or twice a day. Side effects may include drowsiness, dry mouth, and constipation.
Flunarizine is a medication classified as a calcium channel blocker, but with some additional properties [1]. Here's a breakdown of its uses and characteristics:
Main Use:
- Migraine prevention: Flunarizine is primarily used to prevent migraine headaches in adults who experience frequent and severe episodes that haven't responded well to other treatments [1, 2]. It's not used to treat existing migraines.
Other Potential Uses:
- While less common, flunarizine may also be used for vertigo (dizziness), peripheral vascular disease (circulation problems in the legs), and as an add-on therapy for epilepsy [1, 3].
How it Works:
- Flunarizine's mechanism of action for migraines is not fully understood, but it has multiple effects [2]. It acts as a calcium channel blocker, limiting calcium flow into cells, and also has histamine blocking and dopamine receptor blocking properties [1, 3].
Availability:
- It's important to note that flunarizine is not available in the United States or Japan by prescription [2]. In some other countries, it's used for migraine prevention.
Important Considerations:
- Flunarizine can cause drowsiness, weight gain, nausea, and other side effects [2]. If you are considering flunarizine, it's crucial to talk to a healthcare professional about the risks and benefits to see if it's suitable for you.
- Due to its mechanism of action, there can be interactions with other medications. Always disclose all medications you take to your doctor before starting flunarizine.
Remember: This information is for educational purposes only and does not constitute medical advice. Consult a doctor for any questions or concerns you have about flunarizine or any other medication.