Eptinezumab is a prescription medication used to treat migraine headaches in adults. It is an injectable drug, given as an intravenous (IV) infusion. It works by blocking the activity of a protein in the body called calcitonin gene-related peptide (CGRP). This protein is thought to play a role in the development of migraine headaches. Eptinezumab is used on an as-needed basis for the acute treatment of migraine with or without aura. It is not used for the prevention of migraine.
Eptinezumab is a medication used to prevent migraine headaches [Mayo Clinic]. Here's a breakdown of its key features:
- Type of medication: Monoclonal antibody [National Institutes of Health].
- Function: Eptinezumab works by targeting a molecule called calcitonin gene-related peptide (CGRP) which is thought to play a role in migraine headaches [American Migraine Foundation]. By blocking CGRP, eptinezumab can help prevent migraines from occurring.
Treatment:
- Eptinezumab is used for prophylaxis (prevention) of migraines in adults who experience frequent migraine attacks, typically defined as four or more migraine headaches per month [Mayo Clinic].
- It is administered as a self-injection under the skin (subcutaneous injection) typically once every three months [WebMD].
Important things to know:
- Eptinezumab is a relatively new medication and long-term effects are still being studied [Mayo Clinic].
- It can cause side effects like injection site reactions, headache, upper respiratory infection, and fatigue [WebMD].
- Eptinezumab is not suitable for everyone, particularly those with a history of allergic reactions to the medication or its components [Mayo Clinic].
- It is also not recommended for pregnant or breastfeeding women [Mayo Clinic].
Here are some resources for further information:
- Mayo Clinic: https://www.mayoclinic.org/drugs-supplements/eptinezumab-jjmr-intravenous-route/description/drg-20484162
- National Institutes of Health: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8446121/
- American Migraine Foundation: https://americanmigrainefoundation.org/resource-library/anti-cgrp-treatment-options/
- WebMD: https://www.webmd.com/drugs/2/drug-178856/eptinezumab-jjmr-intravenous/details
Disclaimer: I am unable to provide medical advice. If you have any questions about eptinezumab or its use in relation to your migraines, please consult a doctor.