Bithionol is a medication used to treat certain parasitic worm infections, such as schistosomiasis. It works by killing the worms and their eggs. Bithionol is available in tablet form and is taken by mouth. Common side effects of bithionol include nausea, vomiting, diarrhea, abdominal pain, and headache. Serious side effects can include allergic reactions, liver damage, and a decrease in white blood cells.
While Bithionol had past medical uses, it's important to note that it's no longer recommended or widely available due to safety concerns. Here's a summary of its past applications and current status:
Past Uses:
- Antibacterial: Bithionol possessed some antibacterial properties.
- Anthelmintic: It was used to treat parasitic worm infections, particularly liver fluke infestations in animals (sheep and cattle) and tapeworm infections in horses.
- Antifungal: It had some effectiveness against fungal infections.
Important Safety Information:
- Photosensitivity: Bithionol is a potent photosensitizer, meaning it can increase skin sensitivity to sunlight, leading to severe reactions like blistering and burns upon sun exposure.
- Banned for Human Use: Due to the significant photosensitivity risk, Bithionol was banned for use in human medications and cosmetics by regulatory bodies like the US Food and Drug Administration (FDA).
- Limited Veterinary Use: While it might still be found in some veterinary applications in specific regions with restricted use regulations, its use is generally discouraged due to safer alternatives available.
Current Status:
- Not recommended for human or animal use in most regions.
- Safer alternatives are available for treating the conditions Bithionol was previously used for.
Anatomical Therapeutic Chemical Classification
D - Dermatologicals
D10 Anti-acne preparations
D10A - Anti-acne preparations for topical use
D10AB Preparations containing sulfur
ATC Code
Anatomical Therapeutic Chemical Classification
P - Antiparasitic products, insecticides and repellents
P02 Anthelmintics
P02B - Antitrematodals
P02BX Other antitrematodal agents
ATC Code
Anatomical Therapeutic Chemical Classification
QP - Antiparasitic products, insecticides and repellents
QP52 Anthelmintics
QP52A - Anthelmintics
QP52AG Phenol derivatives, including salicylanilides
ATC Code
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Bithionol