Azilsartan medoxomil is an angiotensin II receptor blocker (ARB) used to treat high blood pressure (hypertension). It works by blocking certain natural substances (angiotensin II) in the body that cause the blood vessels to tighten. This results in the blood vessels relaxing, allowing blood to flow more easily and the heart to pump more efficiently. Azilsartan medoxomil is usually taken once a day with or without food. It may be used alone or in combination with other medications to treat high blood pressure.
Azilsartan, also known by the brand name Edarbi, is an angiotensin II receptor blocker (ARB) medication used to treat high blood pressure (hypertension) and heart failure. It works by blocking the effects of the hormone angiotensin II, which causes blood vessels to constrict. Here's a breakdown of its key aspects:
Mechanism of action:
- Angiotensin II is a hormone that naturally causes blood vessels to narrow, leading to increased blood pressure.
- Azilsartan binds to angiotensin II receptors in blood vessel walls, preventing the hormone from attaching and exerting its constricting effect.
- This allows blood vessels to relax and widen, leading to lower blood pressure and improved blood flow.
Applications:
- Primary use: Azilsartan is primarily used to treat essential hypertension (high blood pressure with no identifiable cause).
- Heart failure: It can also be used to treat heart failure by reducing the workload on the heart.
Availability and forms:
- Azilsartan is typically available in tablet form and is available by prescription only.
- The dosage is determined by your doctor based on your individual needs and response to the medication.
Important considerations:
- Azilsartan can cause some side effects, including:
- Dizziness
- Headache
- Fatigue
- Upper respiratory tract infection
- Diarrhea
- Muscle aches
- It is important to tell your doctor about all medications you are taking, including over-the-counter medications and herbal supplements, as they can interact with Azilsartan.
- Pregnancy: Azilsartan is contraindicated during pregnancy and should not be taken.
- Breastfeeding: It is also not recommended for women who are breastfeeding.
- Consult with your doctor before using Azilsartan if you have any underlying medical conditions, such as kidney disease, liver disease, or a history of angioedema (swelling beneath the skin).