Aurotioprol (brand name: Rapamune) is an immunosuppressant drug used to prevent the body from rejecting a transplanted organ. It is usually taken by people who have had an organ transplant, such as a kidney transplant. Aurotioprol works by blocking the body's immune system from attacking the newly transplanted organ. This helps to reduce the risk of organ rejection. Aurotioprol may also be used to treat other conditions, such as rheumatoid arthritis, lupus, and psoriasis.
Aurotioprol, similar to Aurothioglucose, was a medication used in the past to manage rheumatoid arthritis. It belonged to the class of drugs known as gold salts.
Here's a breakdown of Aurotioprol:
- Function: It acted as an antirheumatic agent, meaning it helped alleviate inflammation associated with rheumatoid arthritis.
- Administration: Unlike Aurothioglucose which was injected intramuscularly, Aurotioprol was also administered through intramuscular injections.
- Availability: It was marketed under the brand name Allochrysine by Solvay but has been withdrawn from the market. This is due to the emergence of safer and more effective medications for rheumatoid arthritis.
- Mechanism of action: The precise way Aurotioprol worked is not entirely understood, but it's believed to have suppressed the immune system and reduced inflammation.
- Side effects: Similar to Aurothioglucose, Aurotioprol also carried the risk of various side effects, including skin rash, nausea, vomiting, diarrhea, and potential kidney damage. In rare instances, it could cause a severe condition called agranulocytosis, characterized by a decrease in white blood cells.
Anatomical Therapeutic Chemical Classification
M - Musculo-skeletal system
M01 Anti-inflammatory and antirheumatic products
M01C - Specific antirheumatic agents
M01CB Gold preparations
ATC Code
External Links
Aurotioprol